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Ellen Pompeo, who stars on the hit ABC series "Grey's Anatomy," received a Golden Globe nomination for Best Performance by an Actress in a Television Series - Drama at the 2007 Golden Globe Awards. Along with her fellow "Grey's Anatomy" cast members, she also received the 2007 Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Television Drama.

A Boston native, Pompeo made her major studio film debut in Brad Silberling's "Moonlight Mile," alongside Jake Gyllenhaal, Dustin Hoffman and Susan Sarandon. She went on to star opposite Luke Wilson, Vince Vaughn and Will Ferrell in the wildly successful "Old School" and in Steven Spielberg's "Catch Me If You Can," opposite Leonardo DiCaprio.

Prior to "Moonlight Mile," Pompeo had starred in several independent features, including "In the Weeds" and "Coming Soon."