It seems that March Madness applies not only to basketball, but also to the shenanigans at Seattle Grace Hospital, because it appears that Izzie and George DID have sex and now Izzie thinks their hook-up was "God's plan". After a lot of hangover-induced, guilt-ridden agony from George and squirrelly behavior from Izzie and a very poorly timed visit from Callie's dad, George tells Izzie that he can't tell Callie about their assignation, because it wouldn't be fair to hurt Callie just to ease his conscience. Izzie reluctantly agrees, but does a lot of crying.

As far as everyone else goes, Cristina overly relates to a man who has to have his foot amputated, which somehow leads to her patching it up with Burke, agreeing to have a wedding. Meredith's hair looks awesome, and she successfully performs a bone-grafting procedure under the guidance of McSteamy, despite some overprotectiveness from McDreamy, who seems to be having some kind of post traumatic stress disorder in the wake of Meredith's near-death experience. Meredith's pretty sure her dead mother would be proud of her for this, which is a nice step toward avoiding getting into the kind of emotional state where you let yourself drown. Alex continues to be awesome in general, this week helping Crush choose her new face and admitting to her in the process that his nascent relationship with Addison is "complicated." And everyone else is acting totally batty because they're being interviewed for the Chief position and suspect that Marlowe is going to sweep it out from under them.

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