Teri Hatcher's wildly successful portrayal of Susan Mayer earned her a 2005 Golden Globe Award (Best Actress in a Leading Role, Musical or Comedy, Television), a 2005 Screen Actors Guild Award (Outstanding Performance by a Female Actor in a Comedy Series), a 2006 Golden Globe Award nomination, a 2005 Television Critics Award nomination and a 2005 Emmy Award nomination for Outstanding Lead Actress in a Comedy.

Felicity Huffman has proven herself an exceptional actress in both dramatic and comedic roles. Her role as Lynette has earned her, along with the rest of her cast, the 2005 SAG Award for Outstanding Performance by an Ensemble in a Comedy Series and a 2005 Emmy Award nomination as Best Actress in a Comedy Series.

Marcia Cross is currently in production on the third season of smash hit Desperate Housewives. In 2005 and 2006 she was nominated for a Golden Globe Award in the Best Actress category. She was also nominated for an Emmy Award in the Best Actress in a Comedy Series category in 2005.

Recently named one of People's "50 Most Beautiful" and the "#1 Hottest Woman in the World" on Maxim's 2005 annual "Hot 100" list, Eva Longoria was also voted by Variety as one of the "Ten New Faces to Watch", Rolling Stone's "People of the Year", USA Today's "TV's Hot 11" and TV Guide's "New Faces of Fall". In addition, she just signed an exclusive worldwide contract as the newest face of L'Oreal.

Nicollette Sheridan, born in England and raised in London and Los Angeles, is perhaps best known to TV audiences for portraying the beautiful, powerful and manipulative Paige Matheson in the long-running drama series, Knots Landing. She returns to series television as Edie Britt, the serial divorcee whose romantic conquests keep the neighborhood buzzing on ABC's hit series, Desperate Housewives.

Brenda Strong can be seen - but mostly heard - as Mary Alice Young, the recently departed narrator of Desperate Housewives. A native of Portland, OR, she left home to attend Arizona State University, where she earned a bachelors degree in Musical Theater. After graduation she moved to Los Angeles, where she soon began appearing in television and films.

James Denton has made all of America wish for faulty pipes due to his role as the world's sexiest plumber, Mike Delfino, on ABC's smash hit, Desperate Housewives. Along with the rest of the cast, Denton was honored with the 2006 and 2005 SAG Award for Best Ensemble in a Comedy. He has just completed filming the feature film Wanted: Undead or Alive with Saturday Night Live alum Chris Kattan. The upcoming comedy features Denton and Kattan as Zombie-hunting cowboys in the Wild, Wild West.

Doug Savant first gained national attention when he was cast in the role of Matt Fielding on the Fox series Melrose Place. It marked one of the first times an openly gay character was portrayed on network television. The series, which could only be described as a cultural phenomenon, became a television fixation, continually sparking water cooler conversations week after week.

A native of South Texas, Ricardo Antonio Chavira was born in Austin and raised in San Antonio, where he graduated from Robert E. Lee High School, now the Performing Arts School, and Incarnate Word College. He received his MFA from the highly regarded UC-San Diego's Professional Actor Training Program in 2000, and moved to Los Angeles shortly thereafter. Since that time, he has worked consistently in all areas of the entertainment industry - film, television and theatre.

Andrea Bowen began her life as a professional performer on Broadway in New York at the age of six, playing Young Cosette in Les Miserables the youngest Cosette in the show's 16-year run. She went on to originate the role of Marta Von Trapp in the Original Cast of the Broadway revival of The Sound of Music with Richard Chamberlain, and the role of Adele in the Broadway musical production of Jane Eyre.

Joy Lauren was born and raised in Atlanta, Georgia. She first realised that she wanted to be an actress at age seven and began performing at the Alliance Theater in Atlanta. At age eleven she moved out to Los Angeles with her mother, Nan Jorgensen, to pursue her love of acting.

Kyle MacLachlan is an actor who has brought indelible charm and a quirky sophistication to some of film and television's most memorable roles. He has recently joined the cast of Desperate Housewives, playing Dr. Orson Hodge, Bree's (Marcia Cross) charming new husband who is a dentist with a hidden agenda. Last season he could be seen on In Justice for ABC, playing David Swain, the enigmatic head of an investigation agency specialising in solving cases of the wrongly convicted.