Who are they?
Dr Mike Vlasek, Rock and roll Head of Surgery and recovering morphine addict
Dr Frank Campion (‘Cranky Frank'), Head of ED, Compassionate, vulnerable and the world's worst boss

Who are they? Peter Petrelli, hospice nurse and empathic mimic (he copies other Heroes' superpowers in a really nice way).
Sylar, watchmaker and superpowered psychopath (he steals Heroes' abilities in a really decapitating way).

Who are they?
Michael Scofield, structural engineer and fugitive with a highly complex mind
Alexander Mahone, FBI agent assigned to hunt down Michael and his escapees, puzzle addict and superbrain

Who are they?
Dr. Jack Shephard, spinal surgeon, reluctant leader of the survivors of Oceanic Flight 815
Johnathan 'John' Locke ('Locke'), tracker, hunter, miraculously regained use of legs after crash

Who are they?
Mike Delfino, local plumber, attractive and mysterious
Ian Hainsworth, new man in town, rich and elegant

Who are they?
Wilhelmina Slater, Mode Creative Director, Scheming and power hungry
Daniel Meade, Mode Editor-in-Chief, Ditzy, sweet and well-dressed