Bart arrives for work hungry for distraction. Anything to avoid thinking about the tragedy unfolding at home with Ann-Maree. Frank picks up on this need, and steers him to what at first appears to be a straightforward case of gastro. But appearances deceive and almost before Bart can catch his breath the patient, Emma, has collapsed into Resus and is fighting for her life. Diagnosis after diagnosis fail, and despite his best efforts it looks like this young woman will die under Bart's care. Finally, desperately, Bart hits onto what he hopes is a correct diagnosis, but will it be too late?
Into this tumult enters Dominic (Von's homecare patient) with a bad infection. Charlotte and Gabrielle soon discover the culprit is poor follow-up wound care. Gabrielle alerts Von so she can track down the negligent staff member responsible. But Von's reaction puzzles and angers Gabrielle. It turns out Von was the nurse who avoided Dominic and she won't give a satisfactory reason for her actions.
Gabrielle is lead to suspect Dominic may have assaulted Von, and that Von is covering up so Dominic will not be sent into care. Von denies this but Gabrielle won't let it go. Finally Von tells Gabrielle the cause of her problem, and it involves a terrible secret she's been carrying with her for thirty seven years. A secret that will have an impact on Von's very future in the ED.
To Frank's immense relief, Elizabeth assures him his whistle blower status is safe with her. What Frank doesn't know is she's lying. Elizabeth called Oliver Maroney's office moments after Frank's confession and is just waiting for him to return her call to seal Frank's fate. However, before this call comes through, Elizabeth is witness to a busy day in the ED, and sees Frank's indispensable role within it as doctor, mentor, leader, and shoulder to cry on. Elizabeth is left in no doubt that Frank is the heart and soul of the ED. Will she destroy it all for Oliver Maroney?
Mike's not accustomed to being this nervous. But as hard as he tries to hide it, his impending kidney donation is stripping him of his normal cool. Frank tries to reassure him, telling him he's doing the right thing in the right hospital. Laura, too, strives to set his mind at ease. But as Mike goes to theatre, he's full of apprehension. It is almost as if he is worried about what will occur when he sinks into unconsciousness. And he has reason to be worried. During his operation we go back in time and revisit his and Laura's relationship at different times and critical stages uncovering devastating revelations about their love.