Director of Medicine, Oliver Maroney is on the warpath. He wants to know who leaked critical information to a deceased patient's wife that resulted in a damages suit being launched against the hospital. He wants to know whether Frank had anything to do with the leak and if he did; he wants Frank's head on a platter. Frank won't admit to having leaked the information but he won't deny it either. Frank shows no signs or has no sense of self preservation when he continues to harangue Admin at every opportunity.

Meanwhile, its Dan's first day on the job since he began interferon therapy and he's beginning to exhibit symptoms of irritability, vagueness and fever. When pushed Dan reveals the truth to Gabrielle. Gabrielle is sympathetic but she also has her patients to think of. Dan will have to be very upfront with her about his capabilities to carry out his job. Dan asks Gabrielle not to tell anyone else about the fact he has started interferon. Especially Erica. Gabrielle doesn't think Dan is making the right call here but will abide by his request.

Erica is still shattered by the news that her relationship with Dan is inexplicably over. She tries valiantly not to let this affect her but it's hard. Her day is made more difficult when she has to nurse the patient from hell; paranoid old wart hog -- Dorothea Louden seems intent on making Erica's life a misery.

A closed ICU means that amputee patient Ben Quilty is brought back to the ED. Frank is not happy about the situation. Frank and Dan's attitudes to Ben change when they learn that Ben deliberately caused the accident that led to his amputation. Frank's ready to have the man scheduled but Elizabeth has a different perspective. After talking with Ben and conferring with colleagues she determines that Ben is suffering from a form of Body Integrity Identity Disorder (BIID). Basically Ben has never felt that his left leg has belonged to him. He has always identified as an amputee. Hence the drastic action he took to fulfil his sense of himself. She stresses that now he has lost his leg he will no longer be a danger to himself. In fact he should go on to live an untroubled life. Needless to say Frank finds this very hard to swallow.

As hard as it is for Dan to understand Ben's motivations for wanting to become an amputee, his main beef with Ben is that Ben continues to lie to his girlfriend, Angela White. Feeling guilty about his own lies to Erica and fuelled by the symptoms of interferon Dan gives Ben a hard time. Gabrielle hauls Dan out of Resus and sends him home.

A Mr. Fixit James Byrne, arrives in the ED. While he is repairing equipment James will make a play for Erica.

Mike and Laura's relationship continues to improve while they wait for Simon to undergo dialysis. But Simon's condition worsens. He's in end stage renal failure now. The only way forward is if he has a transplant. Laura expects Mike to give up one of his kidneys. She thinks it's the least he can do for Simon. Mike reluctantly considers it, but he and Frank wonder how he can possibly undergo the operation and recovery period without the aid of pain relief.